Methotrexate Side Effect

Methotrexate is an anti-metabolite drug prescribed to cancer patients amongst others such as arthritis patients etc. Methotrexate is classified as a disease-modifying anti-rheumatic drug because it decreases pain and swelling associated with arthritis, and also, methotrexate can lessen joint damage and lower the risk of long-term disability. Improvement from methotrexate may be seen at six weeks but it may take 12 weeks or even six months of treatment for full benefit to be realized. Methotrexate blocks the enzyme dihydrofolate reductase. By doing so, it affects production of a form of folic acid, which is needed for actively growing cells. Sold as Mexate® and Folex®, methotrexate is also used to treat breast cancer, lung cancer, mesothelioma, non Hodgkin lymphoma, and other cancers. Methotrexate side effects may include nausea, vomiting, diarrhea fatigue, dizziness, hair loss, mouth and/or lip sores, swollen, tender gums, headache, reddening of the eyes and a loss of appetite. Methotrexate also has severe complications in pregnancy and can lead to severe birth defects as it is suspected to be a teratogen. Besides the folic acid deficiency during pregnancy is likely to have its own consequences.

Notably the drug is used in chemotherapy for mesothelioma patients. Therefore the side effects caused by the use of methotrexate are part of the pain and suffering caused by mesothelioma due to asbestos exposure. Ten thousand Americans die every year of asbestos-related diseases including mesothelioma, asbestos lung cancer and asbestosis- all caused as a result of over exposure to asbestos, a fibrous mineral used in construction for insulation and as fire retardant. Asbestos claims pertaining to mesothelioma and other asbestos related diseases are very different from other workplace injuries and constitute a specific area of law. The numbers are staggering coming to about 30 lives per day claimed by asbestos and this does not account for the millions of Americans who are living with asbestos-related diseases.

A mesothelioma or asbestos law firm must be able to take into account all the factors and various complications that the mesothelioma treatment may entail. To do so the law firm has to be resourceful enough and experienced enough to know all the various contingencies that may be involved in a mesothelioma related case. It must therefore also have adequate experience in handling mass torts litigation in federal courts around the country. This is very important because at times local law firms participate in mass torts litigation as a means of trying their hand at getting rich quick. Most of these "boutique" law firms lack in the requisite understanding of the disease and the compensation that a mesothelioma patient requires, especially when his or her condition is compounded by incidental side effects as with the methotrexate. It is essential therefore the law firm you choose must have a history of dealing with mesothelioma claims including claims pertaining to the treatment of mesothelioma which may be as painful as the disease itself. A mesothelioma law firm should be able to assign a lawyer to your case who will be able to travel to you on a regular basis. The lawyer must have the ability to analyze and investigate a potential claim as well as determining who is responsible for your pain and suffering.

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FAQs


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Q:What are the kidney side effects of methotrexate?

A:Methotrexate may be a highly useful drug for in most cases, but some of its side effects have been hard to ignore by patients and some are now wondering if the side effects are really worth the use of this drug. Some of its most common side effects are nausea, vomiting, diarrhea, fatigue, dizziness, hair loss, mouth and/or lip sores, swollen, tender gums, headache, reddening of the eyes and a loss of appetite. Methotrexate is also known to cause severe complications if used during pregnancy, both for the mother and the baby. In some cases the use of Methorexate may also cause irreparable damage to the kidneys as well.

Q:Should methotrexate for arthritis side effects be worrisome for me?

A:Since the 1950s, mainstream medical professionals have resorted to prescribing methotrexate for Arthritis whilst overlooking the side effects. However, the facts reveal that methotrexate is an extremely toxic compound substance that whilst suppressing the signs and symptoms of arthritis, opens a Pandora's Box worth of adverse side-effects. These range from relatively mild ones such as raspy cough and labored breathing to fever, chills and diarrhea as well as urine mixed with blood.

Q:Are there any methotrexate for ectopic pregnancy side effects that I need to be wary off?

A:Methotrexate is used for treating an ectopic pregnancy as if it was going out of style. However, the fact is that with the whole barrage of adverse side-effects caused by the drug, it should go out of style. There is difficulty in breathing and mild abdominal pain on the lighter side and hives, blood vomits, unusual vaginal discharge, vomiting and urine with release of blood on the more serious side.

Q:What are some of the most serious methotrexate injection side effects?

A:Though methotrexate replaced the highly toxic drug aminopterin in the 1950s as the medication for treating arthritis, the cocktail of toxic chemicals in the methotrexate injection has its own set of side effects. Instead of alleviating the root causes of arthritis as well as psoriases, certain forms of lung and breast cancer that it is also used to treat, methotrexate destroys the lining of our gastrointestinal tract and causes diarrhea, pale and rash ridden skin and even jaundice.

Q:What are some of the most serious methotrexate injection side effects?

A:Though methotrexate replaced the highly toxic drug aminopterin in the 1950s as the medication for treating arthritis, the cocktail of toxic chemicals in the latter has its own set of body ailments. Instead of alleviating the root causes of arthritis as well as psoriases, certain forms of lung and breast cancer that it is also used to treat, methotrexate destroys the lining of our gastrointestinal tract and causes diarrhea, pale and rash ridden skin and even jaundice.

Q:Though it is supposed to cure my rheumatoid arthritis, will methotrexate injections' side effects cause other diseases?

A:Contrary to popular opinion and consensus amongst medical professionals, not only does methotrexate not completely cure rheumatoid arthritis but it afflicts the body with a laundry list of complications and ailments. The side effects of methotrexate injections range from pale, itchy and peeling skin, shortness of breath, diarrhea, blood release in stools as well as darkened urine as well as the onset of fever, flu and sore throat.

Q:I am considering treatment with MTX and have heard that there are some serious methotrexate rheumatoid arthritis side effects. Is this true?

A:Ever since methotrexate arrived on the scene in the early 1950s, medical practitioners faced with an arthritis victim have resorted to using it to treat the disease. The ruling of FDA is considered as main regulating agency in the medical industry. The evident side effects of using methotrexate for treating rheumatoid arthritis stem from acute damage being caused to the lining of the gastrointestinal tract.

Q:When undergoing conventional treatment for rheumatoid arthritis, is there just one methotrexate side effect or are there multiple ones?

A:You may find it truly shocking that even though using methotrexate for treating rheumatoid arthritis results in not one side effect but around two dozen known ones, it has been prescribed for use for the past six decades. These include but are not limited to aching muscles, dizziness, loss of appetite, sore throat, fever and flu, paleness of skin that leads to bruising and peeling as well as the release of blood in urine discharge and stools.

Q:Are there any worrisome methotrexate side effects? If so then why is it still in use?

A:Yes, side effects of methotrexate injections range from diarrhea, pale, reddish and peeling skin, labored breathing, bloody urinal and fecal discharge to name a few. The production and usage of methotrexate is big business for the companies that manufacture it, such as Pfizer, as it has been approved by the FDA for treating everything from arthritis to cancer.

Q:I am wondering whether methotrexate side effects ectopic pregnancy occur. Should I be dreading to find out?

A:Tragically yes. Methotrexate, abbreviated as MTX, has been directly linked to premature fetal death. Women who are expecting are strongly warned against going ahead with treatment for ectopic pregnancy with methotrexate due to the serious side effects that are unleashed. Additionally, if the pregnant woman is suffering with psoriasis or rheumatoid arthritis, it's best to avoid it altogether.

Q:I have been suffering with rheumatoid arthritis for a long time and was put on methotrexate by my physician a while back. What are some of the major side effects methotrexate as I am developing some serious symptoms?

A:Drugs such as methotrexate are a powerful cocktail of substances that though seem to alleviate the symptoms of whatever disease that they are targeting on a temporary basis, unleash a whole set of adverse and often dangerous side effects of their own. Methotrexate is no exception and has been directly linked to explosive diarrhea, sore throat, difficulty in breathing, fever and chills to appearance of blood in urine.

Q:What are some of the side effects of methotrexate?

A:Methotrexate is mostly prescribed to cancer patients as an anti-metabolite drug. Methotrexate is a disease-modifying anti-rheumatic drug which decreases pain and swelling. It takes about 6 weeks for the drug to show any improvement, but real improvement might be visible in about 12 weeks or even six months. Methotrexate side effects include nausea, diarrhea fatigue, dizziness, , vomiting, hair loss, mouth and/or lip sores, swollen, tender gums, headache, reddening of the eyes and a loss of appetite. Methotrexate should be avoided during pregnancy since it is known to cause severe birth defects.

Q:Are the side effects of methotrexate for arthritis really that serious so as to be a cause for alarm?

A:Yes, methotrexate that is used for treating arthritis has a laundry list of dangerous side effects that simply cannot be ignored when trying to decided whether to start a course of this drug or not. These complications range from chronic diarrhea, constrained breathing, raspy sensation in throat, chills, rashness and redness of skin, flue and jaundice-like symptoms.

Q:Do the side effects of methotrexate injections pose a serious risk to my health? Though it is meant to treat arthritis, should I refrain from it so as not to further endanger my body?

A:Anything that is injected directly into the blood stream is bypassing our first line of defense as part of our immune system. Methotrexate is a highly toxic drug and is used for treating certain kinds of cancer such as those relating to the breasts, skin, lungs, neck and the head. The side effects of methotrexate injections range from symptoms of jaundice and flu, chills, sore throat, skin rashes and redness and even the discharge of blood in the urine.